Paul G. Ambrose, PharmD, FIDSA

Dr. Paul G. Ambrose is currently the president of the Institute for Clinical Pharmacodynamics (ICPD) in Schenectady, NY. Ambrose is an honorary research fellow for infectious diseases at the Nuffield Department of Medicine at the University of Oxford.  Ambrose’s areas of scientific inquiry primarily involve anti-infective translational science, with the goal of improving patient care through the application of pharmacokinetic-pharmacodynamic (PK-PD) principles. Knowledge gained through the use of non-clinical (in vitro and animal) PK-PD infection models may be leveraged with human pharmacokinetic data in order to discriminate between potential dosing regimens and thereby increase the probability of positive clinical outcomes while minimizing the potential for drug-related toxicities. ICPD has successfully utilized this approach for support of regulatory decision-making and as support for Clinical and Laboratory Standards Institute susceptibility breakpoint determinations. Ambrose is the author of over 110 peer-reviewed scientific publications and approximately 300 scientific abstracts. He has served as an editor for four textbooks- most notably the first and second editions of Antimicrobial Pharmacodynamics in Theory and Clinical Practice. Finally, Ambrose is an editor of Antimicrobial Agents and Chemotherapy.